DOBLE ROLE OF BATHOCUPROINE DISULFONIC ACID AS MULTIWALLED CARBON NANOTUBES DISPERSING AGENT AND COPPER PRECONCENTRATION LIGAND: ANALYTICAL APPLICATIONS FOR THE DEVELOPMENT OF HYDROGEN PEROXIDE AND GLUCOSE ELECTROCHEMICAL SENSORS

GALLAY, PABLO; MARCELA C. RODRIGUEZ; MARCOS EGUILAZ RUBIO; GUSTAVO A. RIVAS

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

ELSEVIER SCIENCE BV

Lugar: Amsterdam; Año: 2020

0731-7085

e are reporting a new strategy for preparing carbon nanotubes (CNTs)-basedhydrogen peroxide and glucose amperometric sensors by taking advantage ofthe dual role of bathocuproine disulfonic acid (BCS) as dispersing agent of multiwalledcarbon nanotubes (MWCNTs) and as ligand for the preconcentration ofCu(II). The platform was obtained by casting glassy carbon electrodes (GCE) withthe dispersion of MWCNTs in BCS (MWCNTs-BCS) followed by thepreconcentration of Cu(II) by surface complex formation at open circuit potential(GCE/MWCNTs-BCS/Cu). The resulting electrode was used for the sensitiveamperometric quantification of hydrogen peroxide at 0.400 V catalyzed by thepreconcentrated copper, with a linear range between 5.0 x 10-7 and 7.4 x 10-6 M,a sensitivity of 24.3 mA.M-1, and a detection limit of 0.2 uM. The adsorption of GOx at GCE/MWCNTs-BCS/Cu followed by theimmobilization of Nafion (Naf), allowed the construction of a sensitive andselective amperometric glucose biosensor with a linea